Tag: Neanderthal

Implications of the 23AndMe Bankruptcy

This post is not a super fact post but it contains some other important information. 23AndMe, the large personal genomics and biotechnology company just went into bankruptcy. This has implications for its 15 million customers including me and my wife. In fact, it is advised that you delete your data from their website, and I will tell you how to do that.

About 23AndMe

23AndMe, founded in 2006 provides a direct-to-consumer genetic testing service in which customers provide a saliva sample that is analyzed to generate reports relating to the customer’s ancestry, genetic predispositions, inherited health conditions and other health related topics. Who doesn’t want to know something about their ancestry going back possibly thousands of years? Who doesn’t want to know about genetic timebombs in their DNA? I took the test, and my wife took the test, our daughter took the test, other family members took the test, and it was fun and very interesting, and a good conversation starter. For example, I found out that I am practically a Neanderthal, well maybe not exactly.

Geneticist sequencing human genome Asset id: 2479929725 by FOTOGRIN

What we did not think about is that 23AndMe represented a significant privacy risk. This is data that can be misused in various ways. You can be discriminated against based on this data, you can be denied employment, insurance companies can use it to deny you health insurance, you can be subject to surreptitious testing without your consent. Not to mention familial complications, such as infidelity, and people finding out who their real parents are, and relatives were. In the wrong hands this data is dangerous.

In October 2023 hackers stole 7 million people’s data. Stolen information included people’s names, addresses and genetic data and was sold online. This made the economic difficulties the company was in even worse. Yesterday the company filed for Chapter 11 bankruptcy and their founder and CEO resigned. Now people are rightfully worried about their data.

Ancestry from 23AndMe

However, the information we got from our genetic tests was interesting and fun. I found out that my ancestry was 99.8% Northwestern European, 85.3% Scandinavian/Sweden/Norway, 14.4% Finnish, 0.1% other Northwestern European, and 0.2% Siberian. Not surprising since my family have lived in northern Sweden and northern Finland since at least 1628 according to the ancestry records. Other people in my family were a lot more mixed than that. I can add that I also thought it was fun to on occasion find second cousins or third cousins whose existence I was unaware of.

I also found out that I had strong Neanderthal ancestry. The report says I have more Neanderthal variants than 99% of customers. On the 23AndMe website there was a forum, or club for people with strong Neanderthal ancestry, so I joined. However, some people were taking it a bit too seriously and after I while I did feel comfortable in the Neanderthal club, so I left.

Reconstruction of a Neanderthal by Natural History Museum. Werner Ustorf, CC BY-SA 2.0 <https://creativecommons.org/licenses/by-sa/2.0&gt;, via Wikimedia Commons

Fun Facts from 23AndMe

I was happy to find that I did not seem to have any hereditary predisposition for any illnesses among the ones they listed. Well, I have the typical predisposition for type II diabetes. I was happy to see that I am not predisposed to get Alzheimer’s, which I was worried about, since I have a couple of relatives with that condition.

The most fun and perhaps least important aspect of the genetic testing was the non-health related predispositions. For example, regarding “ice cream flavor preference” my genes says that I am “more likely to prefer vanilla over chocolate ice cream”. My wife got the opposite, and this is correct. I love vanilla, she loves chocolate. I am less likely than average to be afraid of heights and less likely to be motion sick.

Our eye colors, finger and toe lengths, propensity for dandruff, cheek dimples, hair texture and thickness, earwax type, freckles, bunions, the DNA analysis got it all right. By the way I am good at smelling asparagus, just like my DNA test says. The one thing that my DNA test got wrong was that the most likely time for me to wake up in the morning is 6:53AM. The DNA test got my wife’s wake up time correct, but I am not waking up at 6:53AM.

Deleting your data from 23AndMe

OK this is a lot of fun and maybe useful, but the big question is do we want this information in the wrong hands. I’ve mentioned a few ways in which this data can be misused but there may be many more ways this data can be misused that I have not thought about, that no one has yet thought about. Therefore, I deleted all our data from 23AndMe today. If you are a member of 23AndMe I suggest you do the same. Below I am giving you the instructions for how to delete your data from 23AndMe.

  • Log into your 23andMe account. You may need to reset your password.
  • Go to your profile and locate the little menu up on the far top right. Select Settings.
  • Scroll to the “23andMe Data” section at the bottom of the page and click View (button). If you want to download your data, select what you want to download. I downloaded the “reports summary”, which is a pdf file. I also downloaded ancestry composition raw data, which is a large CSV file compressed into a zip file. Finally, I downloaded family tree data, which is in json format.
  • Scroll to the “Delete Data” section and click Permanently Delete Data. This is a Red button at the bottom.
  • Confirm your request: You’ll receive an email from 23andM. Click the link/button in the email to confirm.

Important Note : I am back from my ski vacation, and I once again respond to comments posting and visiting other people’s blogs.

To see the Super Facts click here

Neanderthals Never Lived in Africa

Super fact 27: Neanderthals never lived in Africa. Neanderthals, or Homo Neanderthalensis, lived in Europe and Asia but never in Africa.

Reconstruction of a Neanderthal by Natural History Museum. Werner Ustorf, CC BY-SA 2.0 <https://creativecommons.org/licenses/by-sa/2.0&gt;, via Wikimedia Commons

It is a common belief that humans originated in Africa. That is true but human ancestry is complicated, and in the past, there were many human species and subspecies. Starting with Homo Erectus, it is estimated that they lived between 1.6 million years ago until about 100,000 years ago.

Homo Erectus was the ancestor of Homo Heidelbergensis (between 700,000 and 200,000 years ago) as well as Homo Floresiensis (hobbit people – between 100,000 and 50,000 years ago). Homo Heidelbergensis in turn was the ancestor of (at least) three homo species, Homo Sapiens (between 300,000 until now), Homo Neanderthalensis (between 400,000 to 40,000 years ago),  and Homo Denisova 300,000 to 25,000 years ago.

However, note that Homo Neanderthalensis is not an ancestor of Homo Sapiens. Homo Heidelbergensis was an ancestor to both. Homo Neanderthalensis originated in Europe and Asia and stayed there, whilst Homo Sapiens originated in Africa and ventured elsewhere (see picture below).

Homo Neanderthalensis and Homo Sapiens (or Homo Sapiens Sapiens) interbred, and so did Homo Denisova and Homo Sapiens, and Homo Neanderthalensis interbred with Homo Denisova. What a mess! I can add that Homo Neanderthalensis and Homo Sapiens were different species, so it may seem strange that they could interbreed.

However, species is a complex concept and at certain points in history you could consider Homo Neanderthalensis and Homo Sapiens to be different subspecies rather than different species. That is why you sometimes hear the terms Homo Sapiens Neanderthalensis and Homo Sapiens Sapiens. Now when you know how complicated it is, I suggest you take a look at the map below.

The spread of Homo Erectus (yellow), Homo Sapiens (red) and Homo Neanderthalensis (dark yellow). NordNordWest, Public domain, via Wikimedia Commons

I can add that genetic testing can reveal how much Neanderthal DNA you have. I took a test with 23AndMe to find out about my ancestry (it was 98% Scandinavian and Finnish) and to find out about my risk for genetic illnesses. 23AndMe also told me that I was in the 99 percentiles with respect to carrying Neanderthal genes, meaning that I had unusually many Neanderthal genes (but not 99%). However, no one has called me a Neanderthal to my face yet.

The Extent of the Neanderthal Habitat

The map below indicates where skeleton remains of Neanderthals had been found as of 2017.

Known Neanderthal range in Europe (blue), Southwest Asia (orange), Uzbekistan (green), and the Altai mountains (violet), as inferred by their skeletal remains (not stone tools). There were 165 such places by 2017. Nilenbert, N. Perrault, auteur du guide complet du canotageI, CC BY-SA 3.0 <http://creativecommons.org/licenses/by-sa/3.0/&gt;, via Wikimedia Commons

Other Neanderthal Facts

There are a lot of other interesting and surprising facts about Neanderthals, such as:

  • They lived in caves, but they also built shelters.
  • They had complex tools and skills, cooked and processed food and created art and jewelry, cooked glue, and had musical instruments (for example a bone flute).
  • Neanderthals not only used fire, they were able to control and maintain fire, and they used it to cook food, make tools, and for warmth and shelter.
  • Neanderthals were stockier and more muscular than modern humans, with broader rib cages and shorter limbs. This helped them conserve heat and survive in the cold environments in Europe and Asia during the ice ages.
  • They might have spoken language.
  • There’s evidence that they were seafaring as far back as 200,000 to 150,000 years ago.
  • Their brains were larger than ours. The braincases of Neanderthal men and women averaged about 1,600 cm3 and 1,300 cm3, respectively, which is considerably larger than the modern human average (1,260 cm3 and 1,130 cm3, respectively).
  • They had medical knowledge. They had knowledge of medicinal plants and well-healed fractures on many bones indicate the setting of splints. They also knew how to treat wounds.
  • They hunted big game.
  • They interbred with modern humans.

The Cause of the Ice Ages

Regarding the Ice Ages, which were a great challenge to Neanderthals, they are caused by earth’s orbital cycles. However, keep in mind that does not mean that orbital cycles are causing the current rapid global warming. NASA keeps track of the orbital cycles, and they should slowly be causing a cool down right now, not a  rapid warming. In addition, if the warming was caused by orbital cycles (or the sun), the upper troposphere would be warming as well as the lower troposphere.

However, what we are seeing is a warming of the lower troposphere and cooling of the upper troposphere consistent with greenhouse gas emissions causing the warming (the blanket effect). To read more about what is causing the current global warming, click here.

Illustration of Milankovitch cycles from MIT’s Climate Primer.

Above from PBS explanation and overview of earth’s three orbital cycles.

Endangered Species

When I was a teenager, I read a few of Jean M. Auels novels about pre-historic humans.  I loved them and I saw the movie. Now I am reading Jacqui Murray’s novels about pre-historic humans. Jacqui Murray’s books are even more fascinating and very realistic and well researched.

The latest Jacqui Murray book I’ve read is Endangered Species, the first book in her new series Savage Lands. This book is set to take place 75,000 years ago among Neanderthals and ancient Homo sapiens. I love all her books, but especially Endangered Species. I was also happy that she included canines as heroes in the book (Ump, White Streak, etc.) I am a dog lover after all. I can add that at the end of the book there are a lot of interesting Neanderthal Facts.

You can read my Amazon review for Endangered Species by clicking here and you can read my Virtual Book Blast post for Endangered Species (promoting this book) by clicking here. All the Virtual Book Blasts for Endangered Species feature interesting Neanderthal facts. To see a few more Virtual Book Blasts for this book click on the links in the list below.

  • Virtual Book Blast for Endangered Species – Darlene Foster – Click here
  • Virtual Book Blast for Endangered Species – Liz Gauffreau – Click here
  • Virtual Book Blast for Endangered Species – Carol Cooks – Click here
  • Virtual Book Blast for Endangered Species – John Howell – Click here
  • Virtual Book Blast for Endangered Species – Booomcha, Kymber Hawke – Click here
Front cover of Endangered Species. Click on the image to go to the Amazon page for the paperback version of the book.
To see the other Super Facts click here